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HIF-2α drives osteoarthritis progression via suppression of the HDAC4-ATF4-CHOP signaling axis

Hypoxia-inducible factor-2α (HIF-2α) is a key regulator of cellular adaptation to hypoxia, but its role in osteoarthritis (OA) remains incompletely defined. This study aimed to investigate the contribution of HIF-2α to OA pathogenesis and the underlying molec…

लेखक: Pinpin Jiang, Hang Wang, Yujia Li, Yuanyu Zhang, Jingrui Huang, Yukun Xu, Dahai Rong, Danni Ruan, Yao Wang, Jie Yuan, Pengcui Li· Plos.org· · २ मिनिटांचे वाचन
HIF-2α drives osteoarthritis progression via suppression of the HDAC4-ATF4-CHOP signaling axis

Hypoxia-inducible factor-2α (HIF-2α) is a key regulator of cellular adaptation to hypoxia, but its role in osteoarthritis (OA) remains incompletely defined. This study aimed to investigate the contribution of HIF-2α to OA pathogenesis and the underlying molec… संपूर्ण बातमीसाठी मूळ स्रोताला भेट द्या.

हा सारांश Plos.org येथून घेतला आहे. संपूर्ण बातमी येथे वाचा:Plos.org